Prediction of Ovarian Response by Antimullerian Hormone in Women with Polycystic Ovarian Syndrome: A Randomized Prospective Study
نویسنده
چکیده
AMH is synthesized specifically by granulose cells of developing ovarian preantral and small antral follicles. Circulating AMH levels in women with PCOS are 2to 3-fold more compared to ovulatory women with normal ovaries [6,7], which denotes to the 2to 3-fold rise in the count of small follicles detected in PCOS. The excessive AMH has been hypothesized to decrease follicle sensitivity to FSH induction and oestradiol production, so hindering follicle selection, resulting in follicular maturation arrest at the small antral phase with the failure to reach maturity.
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